2007年10月13日 星期六
迷有效迷有效
那個,Rahul的compounds真的很猛。我的心情呢,很像大家庭的長媳,生了許多女孩;側房不僅生了女孩並男孩,且是四個超級男孩。(哭)作來作去都沒效,實在是很喪氣;從Modeling看來,我做的那系列確實不討好─就更慘啦─預測不好、做出來也真的不好,能怎樣勒?換個角度想,這將來在paper上會是這樣的討論,"..We designed and synthesized a series of 5 or 6 substiuted ____ compounds, and the inhibition activities against various kinases were evaluated. .. It's found that the 5-substituted compounds were not active, ..." 這就是SAR study (握)
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